Wednesday, 4 April 2012

Over and Out

So there we have it! A comprehensive look at TES that has hopefully answered all of your questions.
There have been an array of studies presented, each commenting on the validity of such a treatment, none more so than Karen Pape. From the beginning, Pape has remained a strong advocate for the use of TES as a treatment for paediatric neurological conditions. A pioneer of this particular treatment, Pape has published multiple papers on the positive effects of TES and in a collaborative effort, has since established the treatment protocol for application. She continues to be a prominent voice on the issue of TES in children with neuromuscular conditions and remains a leader in forward thinking in similar areas of research, as amply demonstrated in her current blog. For more information on these areas, we would recommend visiting http://www.karenpapemd.com/.
Karen Pape. MD

As previously mentioned, TES remains a controversial treatment, to which we can merely provide you with the facts and the opinions of others, but the decision is ultimately yours. After combing through the literature it has become increasingly evident that further long term, large scale investigations are required to scrutinise the effects of TES and provide a definitive answer to the unyielding question… Is TES a useful treatment for paediatric neuromuscular conditions?
In our opinion TES may have a place as an “add on” treatment for some children, however, a comprehensive Physiotherapy regime should be the backbone of any paediatric neuromuscular treatment.

Dosage and Dollars

For many people the idea of attaching any electrical device to a child may seem unsettling. When applied correctly TES consists of a lower dose than most other electrical stimulation treatments which is one of the characteristics that makes it more favourable in children. In fact children themselves have referred to TES as feeling like ‘butterfly kisses’ or a ‘tickle machine’. While these descriptions may quite adequately describe what the child is feeling lets look a little more ‘technically’ at some of the parameters.
Dosage:
As mentioned previously TES is often considered alongside NMES as both are used to treat muscle weakness in similar conditions. The treatment parameters and mechanism of action however are markedly different.
The key characteristic that differentiates TES from other electrical stimulation modalities such as NMES is that it is applied at the patients sensory threshold (2-10mAmps). This means it is applied at an intensity where the child can feel it (tickles or butterfly kisses!) but it does not cause muscle contraction and certainly isn’t painful. When selecting between NMES and TES the initial strength of the muscle should be considered. A grading of 3+/5 or less should be treated with TES. Higher than this and NMES or a combination of daytime NMES and night time TES may be used.
During TES and NMES treatment the total current applied can be the same but the duty cycle differs. Instead of a short duration high intensity stimulus as in NMES, TES provides a longer duration, lower intensity stimulus.
Dosage Parameters for NMES Vs TES. Pape (2004)
Individual treatment sessions occur overnight for 8-12 hours 6 times per week. It can take 6-8 weeks to increase muscle volume and 6-12 months to improve function. This long time to effect may be one of the reasons that many experiments don’t produce meaningful results as they simply aren’t allowing enough time for effects to develop.
Total program length varies greatly between individuals. This has been investigated in children with CP and studies so far suggest that mildly affected children require 18months to 2years and severely affected children require 3-4 years. Secondary treatment may be required during puberty as the body grows and changes rapidly.
Summary Table
Parameter
Value
Intensity
Sensory Threshold; 2-10mAmps
Treatment Duration
8-12 Hours
Treatment Frequency
6x/wk
Time to effect:
·         Muscle Volume
·         Function

6-8Wks
6-12Months
Total Program Duration
18months-4 years


Cost:
As we all know medical bills can add up very very quickly!!! While it would be wonderful to have an unlimited healthcare budget, unfortunately cost is something that has to be considered. The good news is that TES is a cost effective treatment modality. The ability to use it as a home based treatment reduces the cost of health care appointments (not to mention the hassle and cost of driving there!!) – every little bit counts!
The cost of a TES machine itself is about US$825. It can only be ordered by a registered medical professional such as your physiotherapist. As mentioned in previous posts TES must be integrated into an appropriate physiotherapy program in order to turn TES induced muscle growth into functional improvement. The cost of such a program is hugely variable between individuals, practices, treatments and countries.
Unfortunately, in the USA and likely in other areas of the world TES treatment is not subsidised by Medicare due to the inconclusive research base.

With all things considered, if TES is safe and beneficial for an individual child it is one of the more time and cost effective treatment options in today’s physiotherapy world.


References:


Dali, C., Hansen, F., Pedersen, S., Skov, L., Hilden, J., Bjornskov, I., Strandberg, C., Christensen, J., Haugsted, U., Herbst, G. & Luskjser, U. (2002). Threshold electrical stimulation (TES) in ambulant children with CP: a randomized double-blind placebo-controlled clinical trial. Developmental Medicine and Child Neurology, 44, 364-369.

Pape KE. (1997) Therapeutic electrical stimulation (TES) for the treatment of disuse muscle atrophy in cerebral palsy. Pediatr Phys Ther  9 110–112. 

Tuesday, 3 April 2012

Can I or Can’t I?

Hello fellow TES researchers! We have picked over articles and reputable sites in order to gather information in the hopes of enlightening you on the precautions and contraindications of the application of TES. In the following we have found some obvious and not so obvious contraindications (we cannot use this particular treatment), precautions (we need to take care) and some general good sense advice.

The Ideal Candidate:
With TES being one of the less invasive and restrictive treatment options when compared to others such as surgery and bracing, it would be nice to say that it was an appropriate option for all children with motor deficits. However, as the research literature shows the results of TES treatment are quite variable and are limited by contraindications. Perhaps the key to optimising the effectiveness of TES is in selecting the individual children who are likely to benefit. 

Ø  As the treatment regime is lengthy it is important that both the child and the family have the ability and desire to adhere to the program
Ø  Candidates and their support system must be motivated to work hard towards change/improvement
Ø  The severity and type of the child’s disorder must be TES appropriate
Ø  Specific ages where children are most likely to benefit have not yet been established. It has been suggested that during puberty the body is geared up for growth and therefore may respond to TES with a greater increase in muscles bulk

Contraindications and Precautions:
Before the application, any site that is to receive the treatment should be tested for sensitivity. This will include hot-cold and sharp-blunt discrimination tests to ensure the patient has adequate sensory ability to detect any equipment (or practitioner) malfunction. These tests are standard and provide quick and easy feedback to eliminate easily preventable problems. It should be noted that children receiving treatment need to be able to provide appropriate feedback to ensure the TES is received at the correct threshold. Cognitive impairments and infancy may therefore become a contraindication.
The following contraindications are generalized for low level electrical stimulation such as TES;
Ø  Cancerous tissue (malignancy)
Ø  Specialised tissue (e.g eyes and testes)
Ø  Active implants such as pacemakers
Ø  Tissue bleeding
Ø  Broken tissue
Ø  Epilepsy and
Ø  Active epiphysis
Active epiphysis.
Retrieved from: http://www.gla.ac.uk/ibls/US/fab/tutorial/generic/growth4.html

We think the key point is to remember that each child is an individual and needs to be treated and assessed as so. Each will have their own opinions and response to treatment. If a child finds the tingling sensation disrupts their sleep this may hinder their physical and emotional development and hence the cost will ultimately outweigh the benefits. 

Precautions are not absolute but they do dictate the call for diligence while applying TES especially on children. The precautions associated with low level electrical stimulation include;

Ø  Any peripheral neuropathies
Ø  Current pain
Ø  Recent trauma to the treated areas and surrounding tissue
Ø  Devitalised tissue and
Ø  Local circulatory insufficiencies
A noteworthy point is to be cautious with adipose tissue. Unfortunately in today’s society we are seeing an increase incidence in childhood obesity and with treatments such as TES and other electrical stimulation, higher intensities are needed to reach the sensory threshold or stimulate the deep underlying tissues which may cause pain or autonomic reactions.
A good physiotherapist will also;
Ø  Check for redness under the adhesive pad in case of allergies or incomplete adhesion of pad which may cause burns
Ø  Maintain TES device as well as electrodes and adhesive pads
Ø  Apply device to themselves before patient application
Ø  Educate on use at home

Electrode burns.
Retrieved from: http://radiographics.rsna.org/content/24/1/41/F3.expansion.html

Most machines have built in safety features such as an automatic shut off to prevent burns or shocks and an output limiter to prevent overstimulation. Despite the list of contraindications and precautions TES is safe and effective when applied in accordance to guidelines.
 We know this is a lot to process (and this is the short of it!) but hopefully, so far, we have made Michaels Jacksons pre-teen afro seem like a military short back and sides. So again, we have braved the literature, bleary eyes and all, to bring you our digestible summary of specific dosages and costs associated with TES application… Coming Soon!
References: